2. Signaling Pathways
  3. Immunology/Inflammation
  4. Interleukin Related
  5. IL-18 Isoform
  6. IL-18 Inhibitor

IL-18 Inhibitor

IL-18 Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-174270
    NLRP3-IN-79
    		Inhibitor
    NLRP3-IN-79 is a NLRP3 inhibitor. NLRP3-IN-79 inhibits NLRP3 inflammasome with an IC50 of 10.69 nM. NLRP3-IN-79 blocks NLRP3 inflammasome assembly by directly binding to NLRP3 and disrupting the NEK7-NLRP3 interaction. NLRP3-IN-79 can be used for the study of NLRP3-driven diseases model, including systemic inflammation, peritonitis, and colitis.